Cataracts Research Today is a free monthly online journal that collates and summarizes the latest research about Cataracts, including details on surgical procedures, outcomes, causes, treatment.
The associations between single nucleotide polymorphisms of DNA repair genes, DNA damage, and age-related cataract: Jiangsu Eye Study.
Su S, Yao Y, Zhu R, Liang C, Jiang S, Hu N, Zhou J, Yang M, Xing Q, Guan H
Eye Institute, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, China.
Published 14 February 2013 in Invest Ophthalmol Vis Sci, 54(2): 1201-7.
Articles on Cataracts published 11 February 2013:
Capsular adhesion to intraocular lens in highly myopic eyes evaluated in vivo using ultralong-scan-depth optical coherence tomography. Am J Ophthalmol, 155(3): 484-491.e1.
Articles on Cataracts published 4 February 2013:
Copy number variations of DNA repair genes and the age-related cataract: Jiangsu Eye Study. Invest Ophthalmol Vis Sci, 54(2): 932-8.
Articles on Cataracts published 28 January 2013:
Incidence of visual impairment due to cataract, diabetic retinopathy and trachoma in indigenous Australians within central Australia: the Central Australian Ocular Health Study. Clin Experiment Ophthalmol, 41(1): 50-5.
Articles on Cataracts published 23 January 2013:
ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC. Proc Natl Acad Sci U S A, 110(4): 1500-5.
Advances in human genetics are leading to the discovery of new disease-causing mutations at a remarkable rate. Many such mutations, however, occur in genes that encode for proteins of unknown function, which limits our molecular understanding of, and ability to devise treatments for, human disease. Here, we use untargeted metabolomics combined with a genetic mouse model to determine that the poorly characterized serine hydrolase α/β-hydrolase domain-containing (ABHD)12, mutations in which ... [Abstract] [Full-text]
Articles on Cataracts published 22 January 2013:
Metabolic syndrome and risk of age-related cataract over time: an analysis of interval-censored data using a random-effects model. Invest Ophthalmol Vis Sci, 54(1): 641-6.
Articles on Cataracts published 21 January 2013:
Early-onset cataracts, spastic paraparesis, and ataxia caused by a novel mitochondrial tRNAGlu (MT-TE) gene mutation causing severe complex I deficiency: a clinical, molecular, and neuropathologic study. J Neuropathol Exp Neurol, 72(2): 164-75.
Mitochondrial respiratory chain disease is associated with a spectrum of clinical presentations and considerable genetic heterogeneity. Here we report molecular genetic and neuropathologic findings from an adult with an unusual manifestation of mitochondrial DNA disease. Clinical features included early-onset cataracts, ataxia, and progressive paraparesis, with sequencing revealing the presence of a novel de novo m.14685G>A mitochondrial tRNA(Glu) (MT-TE) gene mutation. Muscle biopsy showed ... [Abstract] [Full-text]
Articles on Cataracts published 15 January 2013:
Retinal straylight before and after implantation of the Bag in the Lens IOL. Invest Ophthalmol Vis Sci, 54(1): 396-401.
MicroRNA-204-5p regulates epithelial-to-mesenchymal transition during human posterior capsule opacification by targeting SMAD4. Invest Ophthalmol Vis Sci, 54(1): 323-32.
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